Born in Brescia, Isabella Mottinelli went to high school in her native city, where she discovered theater through an evening course. After graduating in 2017, she got into drama school, attending the Civica Scuola di Teatro Paolo Grassi. While finishing her studies, she obtained her first lead role in the RAI series "Che Dio ci aiuti". She is also starring in the upcoming Amazon Original Italian film "Anni da Cane".