Natasha Ryan got her start in commercials at the age of 2 until the age of 5, when she was selected to play the role of Hope Alice Williams on Days of Our Lives (1965). She remained in the role for 5 years. During her time on "Days", she played Young Sybil in the 1976 film Sybil (1976) starring Sally Field. Other film roles include Kingdom of the Spiders (1977), Mary Jane Harper Cried Last Night (1977), The Amityville Horror (1979), The Day Time Ended (1979), The Entity (1982) and Going Berserk (1983). After leaving "Days of Our Lives", she appeared in sitcom Ladies' Man (1980) from 1980 to 1981. After appearing in "Going Berserk", Natasha left acting.