Born in Indonesia to Cantonese parents, Lo migrated to Hong Kong in his teens, where he attended acting school and in 1962 joined the Shaw Bros. film company. By 1969 he had become the first kungfu superstar, preceding the legendary Bruce Lee. He acted in more than 100 films, usually cast as villains, then turned to directing in the 1980s. For over a decade ending in 1999, Lo was involved in television work in Hong Kong, until failing health forced him into semi-retirement.