Spice was born on August 6, 1982 in Saint Catherine, Jamaica as Grace Latoya Hamilton. While a student in St. Catherine High School, she frequently participated the Jamaica Cultural Development Commission (JCDC) festival in the music category and earned several medals throughout the years. Although she wanted to become a chartered accountant, she decided to pursue a music career. Following that, she enrolled at the Edna Manley College of the Visual and Performing Arts to study music and drama.