Dr. Isobel "Izzie" Stevens : You said before, *I am not your sister*. Do you feel like I was emasculating you? Dr. George O'Malley : No. I'm too masculine to be emasculated. Dr. Isobel "Izzie" Stevens : I'm sorry. Dr. George O'Malley : Guess you put Dr. Model to rest? Dr. Isobel "Izzie" Stevens : Guess I did.

Dr. Isobel "Izzie" Stevens : [Sshe slams down the magazine]  This is who I was. It has nothing to do with who I am now. I'm a physician. A surgeon! And I am just as qualified as any other intern on this floor. So you're just going to have to get over your chauvinist crap and allow me to do my job. Mr. Humphrey : I'm sure you're a very good doctor. Dr. Isobel "Izzie" Stevens : Then what is your problem? Mr. Humphrey : Look, I fantasized about you. About the woman in this photo, whoever she is. I'm not proud of it, but it's a fact. Do you know what they're gonna do to me today? I have cancer. And they're gonna lift up my legs and expose me to the world, and cut out my prostate, and my nerves. Effectively neuter me. So is it so hard to understand that I don't want the woman who is in that photo to witness... my emasculation?

Dr. Miranda Bailey : You wanna tell me what that was all about? Dr. Isobel "Izzie" Stevens : Nothing. He's probably just crazy or something. [she hesitates]  Dr. Isobel "Izzie" Stevens : Bethany Whisper. Dr. Miranda Bailey : What? Dr. Isobel "Izzie" Stevens : Bethany Whisper. I did a new Bethany Whisper lingerie ad, he saw it in a magazine. Dr. Miranda Bailey : You had time to pose for magazines? Dr. Isobel "Izzie" Stevens : No, it was last year, it just came out. Dr. Miranda Bailey : So, because he saw you in a thong... Dr. Isobel "Izzie" Stevens : No! It was not a thong! Dr. Miranda Bailey : You're hiding out in the hallway? Dr. Isobel "Izzie" Stevens : I think it might be easier if you assign another intern. Dr. Miranda Bailey : Izzie, it's not in your job description. You are a doctor. He is a patient. He's your patient! Biopsy these! If they come back positive, I expect to see you in surgery. You're on this! You hear me?

Dr. Isobel "Izzie" Stevens : What self-respecting surgeon wears salmon-colored scrubs?

Dr. Miranda Bailey : Dr. Victor, I'm sorry, but these are viable nerves. We should save them. Dr. Victor : It will take at least an hour longer. And we might not get it all. Dr. Isobel "Izzie" Stevens : [to George]  You know they call him, *limp Harry*. Dr. Miranda Bailey : But his prognosis with chemo is nearly as good, and frankly if you're worried about missing tee time, I'll be more than happy to finish. [Izzie enters the O.R]  Dr. Miranda Bailey : Dr. Stevens? Dr. Victor : Can we help you? Dr. Isobel "Izzie" Stevens : I'm sorry, Dr. Bailey. Dr. Victor, I agree with her. You just can't... You have to save the nerves. Dr. Victor : What? Dr. Isobel "Izzie" Stevens : The nerves. You have to save them. Dr. Miranda Bailey : Dr. Stevens, I can handle this. Dr. Isobel "Izzie" Stevens : No, you told me the most important thing is giving the patient what they want. What Humphrey wants is his erection. Dr. Victor : [to Dr. Bailey]  She's yours. You get her out. Dr. Miranda Bailey : I can't do that, sir. You know how these young puppies are. Dr. Victor : I'm going to tell Richard about both of you. Dr. Miranda Bailey : You do that. In the meantime, why don't we pretend it's you on this table, and give this a try.

Dr. Alex Karev : Why are you helping me? Dr. Isobel "Izzie" Stevens : [yells]  'Cause it's what Jesus would freaking do!

Dr. George O'Malley : This shift is a marathon, not a sprint. Eat. Dr. Isobel "Izzie" Stevens : I can't. Dr. George O'Malley : You should eat something. Dr. Isobel "Izzie" Stevens : You try eating after performing 17 rectal exams. The Nazi hates me. Dr. George O'Malley : The Nazi's a resident. I have attendings hating me.

Dr. Isobel "Izzie" Stevens : Mr. Humphrey? Mr. Humphrey, I'm sorry to wake you. Mr. Humphrey : C'mon. What time is it? Dr. Isobel "Izzie" Stevens : Ten after five. I'm sorry, I just need to do a brief exam. If you could just sit up for one moment. [he sits up]  Dr. Isobel "Izzie" Stevens : Thanks. This might be a little bit cold. So just take a deep breath. [he looks at her funny]  Dr. Isobel "Izzie" Stevens : If you could just take a deep breath. Mr. Humphrey : You're not a doctor! Dr. Isobel "Izzie" Stevens : I'm Dr. Stevens, but you can call me Izzie. I'll be helping Dr. Bailey with your biopsy this morning. Mr. Humphrey : No, I don't think so. No. Dr. Isobel "Izzie" Stevens : Mr. Humphrey, this will just take a moment. Mr. Humphrey : No, get me Dr. Bailey or Dr. Victor. Dr. Isobel "Izzie" Stevens : I- I just need to do a brief... Mr. Humphrey : You don't need to do anything. Is this you? [he shows Izzie a picture in a magazine of herself posing in lingerie]  Mr. Humphrey : Is this you? It is, isn't it? Get out of my room! Dr. Isobel "Izzie" Stevens : Mr. Humphrey... Mr. Humphrey : Get out of my room!

Dr. Alex Karev : Morning, Dr. Model. Dr. Isobel "Izzie" Stevens : Dr. Evil Spawn. Dr. Alex Karev : [he sees a tattoo on her lower stomach]  Ooooh, nice tat. Do they airbrush that out for the catalogs? Dr. Isobel "Izzie" Stevens : I don't know. What do they do for the 666 on your skull?

Dr. George O'Malley : I don't think you understand. Me - gonads! You - ovaries! Dr. Isobel "Izzie" Stevens : Oh, that reminds me. We are out of tampons. Dr. George O'Malley : You're parading through the bathroom in your underwear, while I'm naked in the shower! Dr. Isobel "Izzie" Stevens : Will you add it to your list, please? Dr. George O'Malley : What? Dr. Isobel "Izzie" Stevens : Tampons! Dr. Meredith Grey : To the list. It's your turn. Dr. George O'Malley : I am a man! I don't buy girl products. I don't want to see you walking in while I'm in the shower. And I don't wanna see you in your underwear! Dr. Isobel "Izzie" Stevens : It doesn't bother me, okay? Look at me in my underwear, George. Take your time, it's no big deal.

Dr. Alex Karev : Here's the thing - I like your rack. Dr. Isobel "Izzie" Stevens : God, what is wrong with you? Why do you have to be so - what is wrong with you? Dr. Alex Karev : I like your rack and I'd want them around if I could have them, trust me I would, but it wouldn't be the end of the world if you got rid of them... because really, I'd want *you*. [Izzie slaps him]  Dr. Alex Karev : Ow! What was that for? [she kisses him] 

Dr. George O'Malley : Do you remember when he wallpapered the hospital with pictures of you in your underwear? Dr. Isobel "Izzie" Stevens : Yeah. Yeah, I do. Dr. Alex Karev : It was before I knew you.

Dr. Derek Shepherd : Do you happen to know what time of year neurosurgeons are the busiest, Dr. Stevens? Dr. Isobel "Izzie" Stevens : There's a time of year? Dr. Derek Shepherd : There's no hard or fast rule, but brain injuries tend to pile up around the holidays. Like our friend here. Folks fall off their roofs while they string up lights. Or they go skating for the first time in a decade and break their heads open. And every year people drive through blizzards to get to parties where they kiss germ-infected strangers under poisonous mistletoe. And then they get so drunk that they smash their heads through their windshield on their way home. Like I said, there's no hard or fast rule.

Dr. Isobel "Izzie" Stevens : Here, my share of the grocery money. When are you going? Dr. George O'Malley : Tonight. Dr. Isobel "Izzie" Stevens : Okay. Seriously, George. Please don't... Dr. George O'Malley : Yeah, could we not talk about it here? Dr. Isobel "Izzie" Stevens : What? Tampons? Dr. George O'Malley : Did you not hear a word I said? Dr. Isobel "Izzie" Stevens : You're a man, we know. [everyone in the room starts to laugh]  Dr. Alex Karev : Talk about shrinking the salamander.

Dr. Isobel "Izzie" Stevens : I'm a pretty girl. Dr. Richard Webber : What? Dr. Isobel "Izzie" Stevens : I'm not being arrogant, it's just... it's just kinda a fact. For a long time I made a career for my looks, so I get it. I'm a pretty girl. And not from a certain angle way, in an obvious way. It's the blonde thing, and the big boobs thing. Big boobs are key to obvious pretty, if you know what I'm saying. Dr. Richard Webber : Dr. Stevens... Dr. Isobel "Izzie" Stevens : That's how men see me. I'm not a smart girl or an interesting girl. I'm a pretty girl. The blonde and the boobs confuses guys into thinking that I'm someone else. And I'm used to it. I'm used to them walking away when they realize... but then Denny goes and asks me to marry him. Dr. Richard Webber : Is that why you cut the wires? Dr. Isobel "Izzie" Stevens : He doesn't make me feel like I'm a pretty girl. He makes me feel like... like me. I think he might know me. And so if I did cut the L-Vad wire, and I'm not saying I did, but if I did then no. I don't feel guilty. And I know that I should and I would if it were anybody else. But I can't feel anything but happy.

Dr. George O'Malley : 007. They're calling me 007, aren't they? Izzie & Meredith : No-one's calling you 007. Dr. George O'Malley : I was on the elevator and Murphy whispered 007. Dr. Cristina Yang : Okay, how many times are we going to go through this, George? Five, ten? Give me a number or else I'm gonna hit you. Dr. George O'Malley : Murphy whispered 007 and everyone laughed. Dr. Isobel "Izzie" Stevens : He wasn't talking about you. Dr. George O'Malley : Are you sure? Dr. Meredith Grey : Would we lie to you? Dr. George O'Malley : Yes!

Dr. Isobel "Izzie" Stevens : [standing in the bathroom, outside the shower, where George is]  I reminded you before you went. Dr. George O'Malley : I forgot when I got there. Dr. Isobel "Izzie" Stevens : No. [she opens the shower door]  Dr. Isobel "Izzie" Stevens : No, you were so passive aggressive! Dr. George O'Malley : Naked! I am naked in the shower! Dr. Isobel "Izzie" Stevens : [closes the shower door]  Just tampons, George! I really needed tampons. God! [Meredith enters the bathroom]  Dr. Isobel "Izzie" Stevens : I'm not riding in the same car as him. Dr. Meredith Grey : [looks at Izzie, who is standing in her "Hello Kitty" underwear]  Unless you're going like that, you're not riding with me either. Where are the tampons? Dr. Isobel "Izzie" Stevens : He didn't buy them. Dr. Meredith Grey : [to George]  You didn't buy them? Dr. George O'Malley : Men don't buy tampons! Dr. Isobel "Izzie" Stevens : [opens the shower door again, and George falls over]  You know what? You're gonna have to get over the whole man thing, George! We're women! We have vaginas! Get used to it! [she walks out of the bathroom, leaving George lying on the floor of the shower]  Dr. George O'Malley : I am not your sister! [he slams the shower door] 

Dr. Isobel "Izzie" Stevens : You kissed me. Dr. Alex Karev : Yes, I did. Dr. Isobel "Izzie" Stevens : Should we?... I mean, there's a discussion that we could have... if you wanted to have one? Dr. Alex Karev : Izzie, I kissed you, with tongue, and I plan to do it again and again - get used to it. End of discussion. Dr. Isobel "Izzie" Stevens : Ok.

Dr. Isobel "Izzie" Stevens : [to Alex]  You wanna see it? You really wanna see it? Fine! Let's look at that tattoo up close and personal, shall we? [she rips off her shirt]  Dr. Isobel "Izzie" Stevens : What are these? Oh, my God! Breasts! How does anybody practice medicine hauling these things around? And what have we got back here? Lets see if I remember my anatomy. [takes off her pants]  Dr. Isobel "Izzie" Stevens : Gluts, right? Lets study them, shall we? Gather around and check out the booty that put Izzie Stevens through Med. school! You wanna call me Dr. Model? That's fine. But just remember that while you're all still sitting on 200 grand of student loans, I'm out of debt.

Dr. Alex Karev : Why would you want to help me? Dr. Isobel "Izzie" Stevens : [Yelling]  BECAUSE IT'S WHAT JESUS WOULD FREAKING DO!

Dr. Cristina Yang : You are eight feet tall. Your boobs are perfect. Your hair is down to there. If I was you I would just walk around naked all the time. I wouldn't have a job, I wouldn't have any skills, I wouldn't even know how to read. I would just be... naked. Dr. Isobel "Izzie" Stevens : It's makeup. It's retouching. Dr. Cristina Yang : You get that we hate you, right?

Dr. Cristina Yang : [they all see the Nazi]  That's the Nazi? Dr. George O'Malley : I thought the Nazi would be a man. Dr. Meredith Grey : I thought the Nazi would be... the Nazi. Dr. Isobel "Izzie" Stevens : [Izzie walks up behind them]  Maybe it's professional jealousy. Maybe she's brilliant and they call her a Nazi because they're jealous. Maybe she's nice. Dr. Cristina Yang : Let me guess - you're the model. [Izzie gives her an evil look]  Dr. Isobel "Izzie" Stevens : [to the Nazi]  Hi, I'm Isobel Stevens, but everyone just calls me Izzie. Dr. Miranda Bailey : I have five rules. Memorize them. Rule number one, don't bother sucking up. I already hate you, that's not gonna change.