Leslie Winkle is an en experimental physicist at the California Institute of Technology who works in the same lab as Leonard Hofstadter. She dates Leonard off and on and is clearly the boss in their relationship. She is very similar to him in interests and appearance, but she has more confidence, and is bossy and shallow. She is frequently at odds with Sheldon Cooper. She is very upfront about her sexual needs.Background: She specializes in high energy physics and her belief in loop quantum gravity as the future of physics puts her at odds with the work of Sheldon Cooper. She has said she can't be in a relationship with someone if they don't have the same scientific beliefs.